Correlation between Clinical Outcomes and Baseline CT and CT Angiographic Findings in the SWIFT PRIME Trial.
Publication/Presentation Date
12-1-2017
Abstract
BACKGROUND AND PURPOSE: Patient selection for endovascular therapy remains a great challenge in clinic practice. We sought to determine the effect of baseline CT and angiography on outcomes in the Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) trial and to identify patients who would benefit from endovascular stroke therapy.
MATERIALS AND METHODS: The primary end point was a 90-day modified Rankin Scale score of 0-2. Subgroup and classification and regression tree analysis was performed on baseline ASPECTS, site of occlusion, clot length, collateral status, and onset-to-treatment time.
RESULTS: Smaller baseline infarct (
CONCLUSIONS: While benefit was seen with endovascular therapy across multiple subgroups, the greatest response was observed in patients with a small baseline core infarct, excellent collaterals, and early treatment.
Volume
38
Issue
12
First Page
2270
Last Page
2276
ISSN
1936-959X
Published In/Presented At
Jadhav, A. P., Diener, H. C., Bonafe, A., Pereira, V. M., Levy, E. I., Baxter, B. W., Jovin, T. G., Nogueira, R. G., Yavagal, D. R., Cognard, C., Purcell, D. D., Menon, B. K., Jahan, R., Saver, J. L., Goyal, M., & SWIFT PRIME investigators (2017). Correlation between Clinical Outcomes and Baseline CT and CT Angiographic Findings in the SWIFT PRIME Trial. AJNR. American journal of neuroradiology, 38(12), 2270–2276. https://doi.org/10.3174/ajnr.A5406
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
29025724
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article