Title

Venous valvular assessment after retrograde catheterization.

Publication/Presentation Date

7-1-1996

Abstract

PURPOSE: To determine whether retrograde passage of a coaxial infusion system (Mewissen-Katzen catheter and guide wire) into extremity veins with valves causes damage.

MATERIALS AND METHODS: Retrograde common femoral vein puncture and passage of an infusion wire-catheter system through the superficial femoral and popliteal veins of one leg were performed in five anesthetized pigs. Heparinized saline was then infused via the catheter and wire for approximately 8 hours. The pigs were then killed, and the femoropopliteal veins were removed from both legs of each pig and examined by a pathologist. The noncatheterized leg veins served as a control in each animal.

RESULTS: Valvular damage occurred in one of five pigs. This may have resulted from leg movement during catheter passage in this animal.

CONCLUSION: Retrograde passage of a catheter-guide-wire infusion system caused minimal to no damage to the venous valves of pigs. This suggests that human venous valves may be spared injury during catheter-directed venous thrombolysis. Further study of catheter manipulation in a model of deep venous thrombosis is needed.

Volume

7

Issue

4

First Page

595

Last Page

597

ISSN

1051-0443

Disciplines

Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology

PubMedID

8855543

Department(s)

Department of Radiology and Diagnostic Medical Imaging

Document Type

Article

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