Department of Surgery; Fellows and Residents; USF-LVHN SELECT Program Students
instillation, mepitel, negative pressure wound therapy, pyoderma gangrenosum, rheumatoid arthritis
Pyoderma gangrenosum (PG) is a rare skin disorder primarily treated with immunosuppression medication. We report a case of a large, chronic PG wound treated with adjunct negative pressure wound therapy with instillation and dwell time (NPWTi-d) using nonadherent dressing (Mepitel) and reticular open-cell foam with through holes (ROCF-CC) with positive outcomes. The patient was a 62-year-old female with rheumatoid arthritis, Hashimoto's thyroiditis, lymphedema, and morbid obesity who presented with a 19.5 cm x 13.2 cm x 2.1 cm wound of three years duration on the right posterolateral lower extremity that successfully responded to a multimodality approach of immunosuppression and wound vac therapy. We conclude in our case that NPWTi-d with Mepitel and ROCF-CC enhanced the wound healing process, and we discuss NPWTi-d's potential role and benefit as an adjunctive therapy option for chronic and poorly controlled PG on patients taking concurrent immunosuppression.
Lee, F. G., Song, E., Wallace, S. J., Shaughnessy, T. J., Raj, M., Teixeira, R., Miles, M. G., & Wojcik, R. (2021). Non-surgical Management of Complex Refractory Pyoderma Gangrenosum With Negative Pressure Wound Therapy With Instillation. LVHN Scholarly Works. Retrieved from https://scholarlyworks.lvhn.org/research-historical-works/23