Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model.
We investigated the effects of anti-CD80/86 antibodies in a murine high-risk corneal transplantation rejection model. A mixed lymphocyte reaction (MLR) assay was conducted with anti-CD80/86 antibodies. Inflammatory cytokine levels in the culture supernatant were measured using an enzyme-linked immunosorbent assay. Interferon (IFN)-γ-producing CD4
Published In/Presented At
Zhu, J., Inomata, T., Nakamura, M., Fujimoto, K., Akasaki, Y., Fujio, K., Yanagawa, A., Uchida, K., Sung, J., Negishi, N., Nagino, K., Okumura, Y., Miura, M., Shokirova, H., Kuwahara, M., Hirosawa, K., Midorikawa-Inomata, A., Eguchi, A., Huang, T., Yagita, H., … Murakami, A. (2022). Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model. Scientific reports, 12(1), 4853. https://doi.org/10.1038/s41598-022-08949-9
Medical Education | Medicine and Health Sciences
USF-LVHN SELECT Program, USF-LVHN SELECT Program Students