Preoperative leukopenia does not affect outcomes in cancer patients undergoing elective and emergent abdominal surgery: A brief report.
Publication/Presentation Date
7-1-2020
Abstract
BACKGROUND: Leukopenic patients have historically been considered poor surgical candidates due to a perceived increase in operative morbidity and mortality.
METHODS: Retrospective cohort study using the NSQIP database to identify adult patients who received chemotherapy for malignancy within 30-days prior to elective or emergent abdominal surgery between 2008 and 2011. Leukopenia was defined as < 4000 WBC/mm
RESULTS: Of the 4369 patients included, 20.2% had preoperative leukopenia. Emergency cases comprised 36.2% of cases. Overall 30-day mortality was 12.2% and 30-day composite morbidity was 29.8%. After controlling for significant confounders, including emergency status, leukopenia was not significantly associated with either postoperative mortality (p = 0.14) or morbidity (p = 0.17).
CONCLUSIONS: Our study suggests that in cancer patients undergoing chemotherapy, leukopenia is not associated with morbidity or mortality and should not influence operative planning in either the elective or emergent setting.
Volume
220
Issue
1
First Page
132
Last Page
134
ISSN
1879-1883
Published In/Presented At
Grant, H. M., Davis, L. L., Garb, J., Arenas, R. B., & Stefan, M. S. (2020). Preoperative leukopenia does not affect outcomes in cancer patients undergoing elective and emergent abdominal surgery: A brief report. American journal of surgery, 220(1), 132–134. https://doi.org/10.1016/j.amjsurg.2019.10.031
Disciplines
Medicine and Health Sciences
PubMedID
31703837
Department(s)
Department of Surgery
Document Type
Article