Title

Optimal Reversal of Novel Anticoagulants in Trauma.

Publication/Presentation Date

1-1-2017

Abstract

The incidence of patients with trauma on novel oral anticoagulants (NOACs) for the treatment of thromboembolic disorders is increasing. In severe bleeding or hemorrhage into critical spaces, urgent reversal of this underlying pharmacologic coagulopathy becomes paramount. Optimal reversal strategy for commonly used NOACs is still evolving. Basic tenets of evaluation of patients with trauma and resuscitation remain the same. Clinical outcomes data in bleeding human patients with trauma are lacking, but are needed to establish efficacy and safety in these treatments. This article summarizes the available evidence and provides the optimal reversal strategy for bleeding patients with trauma on NOACs.

Volume

33

Issue

1

First Page

135

Last Page

152

ISSN

1557-8232

Disciplines

Medicine and Health Sciences

PubMedID

27894493

Department(s)

Department of Surgery

Document Type

Article

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