Blunt cardiac trauma: the effect of alcohol on survival and metabolic function.
Publication/Presentation Date
1-1-1980
Abstract
Cardiac mitochondria showed significant uncoupling of oxidative phosphorylation after rats were given intraperitoneal alcohol. The rate of oxygen utilization in the absence of ADP was increased while there was no significant change in oxygen utilization in the presence of ADP. These in vivo results were confirmed with in vitro experiments. Also, intraperitoneal alcohol increased the mortality of blunt cardiac trauma. The alterations in cardiac energy metabolism demonstrated may explain the increased mortality in alcohol-pretreated animals subjected to cardiac contusion.
Volume
20
Issue
1
First Page
58
Last Page
60
ISSN
0022-5282
Published In/Presented At
Nicholas, G. G., & DeMuth, W. E., Jr (1980). Blunt cardiac trauma: the effect of alcohol on survival and metabolic function. The Journal of trauma, 20(1), 58–60.
Disciplines
Medicine and Health Sciences
PubMedID
7351680
Department(s)
Department of Surgery
Document Type
Article