Title

Report of two patients with hypertrophic pyloric stenosis and Hirschsprung's disease. Coincident or common etiology?

Publication/Presentation Date

8-1-1985

Abstract

Although the etiologies of Hirschsprung's disease and infantile hypertrophic pyloric stenosis remain unclear, it is certain that in Hirschsprung's disease, there is an absence of myenteric ganglia. In pyloric stenosis, there is a decreased number of ganglia, but this may be secondary phenomenon. The occurrence of both Hirschsprung's disease and pyloric stenosis in any single patient is uncommon, disputing a common etiology on statistical grounds. The authors have recently seen two infants with both diseases, and have reviewed the histology and pathophysiology analyzing the possibility of a single cause.

Volume

51

Issue

8

First Page

480

Last Page

481

ISSN

0003-1348

Disciplines

Medicine and Health Sciences

PubMedID

4026078

Department(s)

Department of Surgery

Document Type

Article

COinS