Role of Recombinant Human Bone Morphogenetic Protein-2 on Hindfoot Arthrodesis.
Publication/Presentation Date
12-1-2016
Abstract
Despite advances in understanding bone healing physiology and surgical techniques, delayed union and nonunion still occur after the treatment of hindfoot arthrodesis. There is increasing appeal of bone morphogenetic proteins (BMPs) owing to the innate osteoinductive abilities of BMPs. Effective treatment with BMPs has been shown in animal studies. Human clinical studies have also shown success. The only study investigating the use of recombinant human BMP (rhBMP)-2 in hindfoot arthrodesis found a significant increase in fusion rate. Treatment cost effective. Complications from their use remain low. rhBMP-2 is a safe and effective bone-healing adjunct in hindfoot arthrodesis surgery.
Volume
21
Issue
4
First Page
793
Last Page
802
ISSN
1558-1934
Published In/Presented At
Hreha, J., Krell, E. S., & Bibbo, C. (2016). Role of Recombinant Human Bone Morphogenetic Protein-2 on Hindfoot Arthrodesis. Foot and ankle clinics, 21(4), 793–802. https://doi.org/10.1016/j.fcl.2016.07.001
Disciplines
Medicine and Health Sciences
PubMedID
27871412
Department(s)
Department of Surgery
Document Type
Article