Review of vascular leiomyosarcoma and report of a case localized to the greater saphenous vein of the ankle.

Christopher Bibbo DO, DPM, Lehigh Valley Health Network
Marcus Schroeder

Abstract

Smooth muscle sarcomas involving blood vessels, leiomyosarcomas, are rare, making up less than 2% of all leiomyosarcomas. Leiomyosarcoma of the saphenous vein is even more uncommon, with nearly all cases reported occurring in the thigh. This article reviews leiomyosarcoma of blood vessels and reports on a 62-year-old woman with an extremely rare case of a leiomyosarcoma of the distal portion of the greater saphenous at the ankle.