Arterial and venous strokes in the setting of COVID-19.
Publication/Presentation Date
9-1-2020
Abstract
BACKGROUND AND PURPOSE: Coronavirus disease 2019 (COVID-19) is a global pandemic that causes flu-like symptoms. There is a growing body of evidence suggesting that both the central and peripheral nervous systems can be affected by SARS-CoV-2, including stroke. We present three cases of arterial ischemic strokes and one venous infarction from a cerebral venous sinus thrombosis in the setting of COVID-19 infection who otherwise had low risk factors for stroke.
METHODS: We retrospectively reviewed patients presenting to a large tertiary care academic US hospital with stroke and who tested positive for COVID-19. Medical records were reviewed for demographics, imaging results and lab findings.
RESULTS: There were 3 cases of arterial ischemic strokes and 1 case of venous stroke: 3 males and 1 female. The mean age was 55 (48-70) years. All arterial strokes presented with large vessel occlusions and had mechanical thrombectomy performed. Two cases presented with stroke despite being on full anticoagulation.
CONCLUSIONS: It is important to recognize the neurological manifestations of COVID-19, especially ischemic stroke, either arterial or venous in nature. Hypercoagulability and the cytokine surge are perhaps the cause of ischemic stroke in these patients. Further studies are needed to understand the role of anticoagulation in these patients.
Volume
79
First Page
60
Last Page
66
ISSN
1532-2653
Published In/Presented At
Kananeh, M. F., Thomas, T., Sharma, K., Herpich, F., Urtecho, J., Athar, M. K., Jabbour, P., & Shah, S. O. (2020). Arterial and venous strokes in the setting of COVID-19. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 79, 60–66. https://doi.org/10.1016/j.jocn.2020.07.005
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
33070919
Department(s)
Administration and Leadership
Document Type
Article