Recurrent intracranial myoepithelioma: clinical course and long-term follow-up. Illustrative case.
Publication/Presentation Date
5-5-2025
Abstract
BACKGROUND: Intracranial myoepithelial carcinomas are exceedingly rare tumors associated with a poor prognosis. A review of the literature revealed only 6 published cases, none of which include follow-up longer than 2 years.
OBSERVATIONS: A 26-year-old female presented with headaches, fatigue, and vision changes. She was found to have a rare intracranial myoepithelioma in the parafalcine region. Over the next 7 years, she experienced multiple recurrences managed with surgery and radiation therapy. The patient eventually became pregnant, and a new lesion was identified in her first trimester. Following close observation and a cesarean section, the rapidly growing lesion wasresected, and consistent with prior myoepithelioma.
LESSONS: The authors present the seventh case of primary, intracranial malignant myoepithelioma and the only such case with follow-up longer than 2.5 years. With aggressive management, patients navigating intracranial myoepithelial carcinoma can experience robust survival with conserved quality of life. https://thejns.org/doi/10.3171/CASE25136.
Volume
9
Issue
18
ISSN
2694-1902
Published In/Presented At
Wierzbicki, M., Shelley, I., Mahtabfar, A., & Judy, K. D. (2025). Recurrent intracranial myoepithelioma: clinical course and long-term follow-up. Illustrative case. Journal of neurosurgery. Case lessons, 9(18), CASE25136. https://doi.org/10.3171/CASE25136
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
40324335
Department(s)
Administration and Leadership
Document Type
Article