Prenatally Diagnosed Aggressive Intracranial Immature Teratoma-Clinicopathological Correlation.

Authors

• Hiroki Nariai
• Dana E Price
• Ajit Jada
• Lauren Weintraub
• Karen M Weidenheim
• William A Gomes
• Adam S Levy
• Rick Abbott
• Fatema Malbari

Publication/Presentation Date

1-1-2016

Abstract

OBJECTIVE: To describe clinicopathological correlation of congenital intracranial immature teratoma.

METHODS: A retrospective case analysis from a tertiary medical center.

RESULTS: We report a case of an intracranial immature teratoma detected prenatally at 35 weeks of gestation. The tumor showed rapid growth, causing acute hydrocephalus requiring subsequent ventriculoperitoneal shunting. Resective surgery was performed within 2 weeks after birth. The infant died at day of life 29. Histological examination revealed an immature teratoma, with high MIB1/Ki-67 proliferation index.

CONCLUSION/IMPLICATIONS: Intracranial immature teratoma with high MIB1/Ki-67 proliferation index may serve as an independent poor prognostic factor.

Volume

35

Issue

4

First Page

260

Last Page

264

ISSN

1551-3823

Published In/Presented At

Nariai, H., Price, D. E., Jada, A., Weintraub, L., Weidenheim, K. M., Gomes, W. A., Levy, A. S., Abbott, R., & Malbari, F. (2016). Prenatally Diagnosed Aggressive Intracranial Immature Teratoma-Clinicopathological Correlation. Fetal and pediatric pathology, 35(4), 260–264. https://doi.org/10.3109/15513815.2016.1172687

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

27158748

Department(s)

Administration and Leadership

Document Type

Article