Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group.
Publication/Presentation Date
8-1-2016
Abstract
Management approaches for patients in the emergency department (ED) who present with acute heart failure (AHF) have largely focused on intravenous diuretics. Yet, the primary pathophysiologic derangement underlying AHF in many patients is not solely volume overload. Patients with hypertensive AHF (H-AHF) represent a clinical phenotype with distinct pathophysiologic mechanisms that result in elevated ventricular filling pressures. To optimize treatment response and minimize adverse events in this subgroup, we propose that clinical management be tailored to a conceptual model of disease based on these mechanisms. This consensus statement reviews the relevant pathophysiology, clinical characteristics, approach to therapy, and considerations for clinical trials in ED patients with H-AHF.
Volume
22
Issue
8
First Page
618
Last Page
627
ISSN
1532-8414
Published In/Presented At
Collins, S. P., Levy, P. D., Martindale, J. L., Dunlap, M. E., Storrow, A. B., Pang, P. S., Albert, N. M., Felker, G. M., Fermann, G. J., Fonarow, G. C., Givertz, M. M., Hollander, J. E., Lanfear, D. J., Lenihan, D. J., Lindenfeld, J. M., Peacock, W. F., Sawyer, D. B., Teerlink, J. R., & Butler, J. (2016). Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group. Journal of cardiac failure, 22(8), 618–627. https://doi.org/10.1016/j.cardfail.2016.04.015
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
27262665
Department(s)
Administration and Leadership
Document Type
Article