Carotid Revascularization in Older Adults: A Systematic Review and Meta-Analysis.
Publication/Presentation Date
6-1-2019
Abstract
BACKGROUND: Results from studies comparing carotid artery endarterectomy (CEA) with carotid artery stenting (CAS) in the elderly population are variable in the literature. The objective of this study was to investigate whether CEA or CAS is associated with a better safety profile in older adults (>80 years of age) for treatment of symptomatic and asymptomatic stenosis.
METHODS: A random-effects meta-analysis was performed, and the I
RESULTS: Nine studies comprising 5955 patients were included in this meta-analysis. No differences were identified in terms of 30-day stroke (CEA: 5.8% [n = 257/4415]; CAS: 10.5% [n = 81/767]; odds ratio [OR], 0.57; 95% confidence interval [CI], 0.30-1.08; I
CONCLUSIONS: This study shows that CEA is associated with a statistically significant lower risk of 30-day stroke in the elderly population compared with transfemoral CAS with distal or proximal protection. No differences were noted in the rates of periprocedural TIA, MI, death, and cranial nerve injury between CEA and CAS in the original pooled analysis.
Volume
126
First Page
656
Last Page
663
ISSN
1878-8769
Published In/Presented At
Texakalidis, P., Chaitidis, N., Giannopoulos, S., Giannopoulos, S., Machinis, T., Jabbour, P., Rivet, D., Reavey-Cantwell, J., & Rangel-Castilla, L. (2019). Carotid Revascularization in Older Adults: A Systematic Review and Meta-Analysis. World neurosurgery, 126, 656–663.e1. https://doi.org/10.1016/j.wneu.2019.02.030
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
30797928
Department(s)
Administration and Leadership
Document Type
Article