Importance of First Pass Reperfusion in Endovascular Stroke Care - Insights From Thrombectomy and Aneurysm Registry (STAR).
Publication/Presentation Date
11-1-2022
Abstract
BACKGROUND: Mechanical thrombectomy has become the first-line treatment strategy for patients with large-vessel occlusion strokes. Often >1 thrombectomy maneuver is necessary to achieve reperfusion. A first-pass (FP) effect with improved functional outcomes after mechanical thrombectomy has been described. Aim of the present study is to investigate the FP effect in a large, international, multicenter stroke database.
METHODS: Patients who underwent mechanical thrombectomy for large-vessel occlusion stroke in the anterior cerebral circulation between January 2014 and January 2021 and achieved complete reperfusion were identified from the STAR (Stroke Thrombectomy and Aneurysm Registry). We compared functional outcomes of patients with FP (defined as modified treatment in cerebral ischemia score 3 after a single thrombectomy maneuver) versus multiple-pass complete reperfusion (defined as modified treatment in cerebral ischemia 3 after ≥1 thrombectomy maneuver).
RESULTS: A total of 1481 patients with anterior circulation large-vessel occlusion stroke and successful recanalization were included in the analysis. FP complete recanalization was achieved in 778 patients versus 703 patients with multiple-pass complete reperfusion. Patients with FP complete recanalization had higher Alberta Stroke Programme Early CT [Computed Tomography] Score at baseline (9 [7-10] versus 8 [7-10];
CONCLUSIONS: This analysis of a large, multicenter stroke database confirms the importance of FP reperfusion in endovascular stroke care.
Volume
2
Issue
6
First Page
000427
Last Page
000427
ISSN
2694-5746
Published In/Presented At
Maier, I. L., Almallouhi, E., Psychogios, M. N., Liman, J., Kasab, S. A., Alawieh, A., Chalhoub, R., Wolfe, S., Arthur, A., Shaban, A., Dumont, T., Kan, P., Kim, J. T., De Leacy, R., Osbun, J., Rai, A., Jabbour, P., Howard, B. M., Park, M., Starke, R. M., … STAR Investigators (2022). Importance of First Pass Reperfusion in Endovascular Stroke Care - Insights From Thrombectomy and Aneurysm Registry (STAR). Stroke (Hoboken, N.J.), 2(6), e000427. https://doi.org/10.1161/SVIN.122.000346
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
41582973
Department(s)
Administration and Leadership
Document Type
Article