Safety and Efficacy of MCA-M2 Thrombectomy in Delayed Time Window: A Propensity Score Analysis From the STAR Registry.
Publication/Presentation Date
5-1-2023
Abstract
BACKGROUND: Mechanical thrombectomy of middle cerebral artery M2 segment occlusion of the middle cerebral artery has reported safety and efficacy in recent post-hoc and observational studies. However, there is no known benefit of mechanical thrombectomy for patients with M2 segment occlusions in the delayed time window (>6 hours).
METHODS: The Stroke Thrombectomy and Aneurysm Registry (STAR) is a prospective, multicenter, nonrandomized observational study registry for acute ischemic stroke thrombectomy and aneurysm treatment. We analyzed all patients who underwent mechanical thrombectomy within the late time window (>6 hours from symptom onset) involving isolated M2 occlusions. We used propensity score matching to select a comparison group of patients who underwent mechanical thrombectomy for M1 occlusion in the same time window.
RESULTS: Of 1083 consecutive patients analyzed, propensity matching yielded 180 well matched M1 and M2 pairs. Baseline demographics were well balanced between the groups (M1 and M2). Alberta stroke program early CT score (7.6±1.7 versus 8.3±1.5;
CONCLUSION: In our analysis of the Stroke Thrombectomy and Aneurysm Registry, M2 occlusions not only achieved similar rates of recanalization and good functional outcome compared with M1 occlusions in a delayed time window (6-24 hours from last normal) but also had less symptomatic intracranial hemorrhage.
Volume
3
Issue
3
First Page
000664
Last Page
000664
ISSN
2694-5746
Published In/Presented At
Limaye, K., Koo, A. B., de Havenon, A., Kasab, S. A., Bohnstedt, B., Maier, I. L., Psychogios, M. N., Wolfe, S., Arthur, A., Kan, P., Kim, J. T., Leacy, R., Osbun, J., Rai, A., Jabbour, P., Park, M., Crosa, R., Mascitelli, J., Levitt, M. R., Polifka, A., … Stroke Thrombectomy and Aneurysm Registry (STAR) Collaborators (2023). Safety and Efficacy of MCA-M2 Thrombectomy in Delayed Time Window: A Propensity Score Analysis From the STAR Registry. Stroke (Hoboken, N.J.), 3(3), e000664. https://doi.org/10.1161/SVIN.122.000664
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
41584984
Department(s)
Administration and Leadership
Document Type
Article