Association of Pneumonia, Wound Infection, and Sepsis with Clinical Outcomes after Acute Traumatic Spinal Cord Injury.
Publication/Presentation Date
11-1-2019
Abstract
Pneumonia, wound infections, and sepsis (PWS) are the leading causes of acute mortality after traumatic spinal cord injury (SCI). However, the impact of PWS on neurological and functional outcomes is largely unknown. The present study analyzed participants from the prospective North American Clinical Trials Network (NACTN) registry and the Surgical Timing in Acute SCI Study (STASCIS) for the association between PWS and functional outcome (assessed as Spinal Cord Independence Measure subscores for respiration and indoor ambulation) at 6 months post-injury. Neurological outcome was analyzed as a secondary end-point. Among 1299 participants studied, 180 (14%) developed PWS during the acute admission. Compared with those without PWS, participants with PWS were mostly male (76% vs. 86%;
Volume
36
Issue
21
First Page
3044
Last Page
3050
ISSN
1557-9042
Published In/Presented At
Jaja, B. N. R., Jiang, F., Badhiwala, J. H., Schär, R., Kurpad, S., Grossman, R. G., Harrop, J. S., Guest, J. D., Toups, E. G., Shaffrey, C. I., Aarabi, B., Boakye, M., Fehlings, M. G., & Wilson, J. R. (2019). Association of Pneumonia, Wound Infection, and Sepsis with Clinical Outcomes after Acute Traumatic Spinal Cord Injury. Journal of neurotrauma, 36(21), 3044–3050. https://doi.org/10.1089/neu.2018.6245
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
31007137
Department(s)
Administration and Leadership
Document Type
Article