North American Clinical Trials Network for Spinal Cord Injury Registry: Methodology and Analysis.
Publication/Presentation Date
9-1-2023
Abstract
The North American Clinical Trials Network (NACTN) for Spinal Cord Injury (SCI) is a consortium of neurosurgery departments at university affiliated hospitals with medical, nursing, and rehabilitation personnel who are skilled in the assessment, evaluation, and management of SCI. NACTN was established with the goal of consistently advancing the quality of life of people with SCI through clinical trials of new therapies that provide robust evidence of safety and effectiveness. A prospective multi-center Registry was created to collect the natural course of the acute traumatic SCI patient from time of injury to 12 months follow-up. NACTN's network of hospitals enrolls a significant number of patients, defines and adheres to standard protocols, and provides the infrastructure and highly skilled personnel to conduct trials of therapy for SCI. Registry data have been used by academic institutions and by the biotechnology and pharmaceutical sectors to create comparison datasets for Phase I clinical trials of new therapies.
Volume
40
Issue
17-18
First Page
1817
Last Page
1822
ISSN
1557-9042
Published In/Presented At
Toups, E. G., Ugiliweneza, B., Howley, S. P., Neal, C. J., Harrop, J. S., Guest, J. D., Grossman, R. G., & Fehlings, M. G. (2023). North American Clinical Trials Network for Spinal Cord Injury Registry: Methodology and Analysis. Journal of neurotrauma, 40(17-18), 1817–1822. https://doi.org/10.1089/neu.2022.0403
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
37125443
Department(s)
Administration and Leadership
Document Type
Article