MGMTai: O6-methylguanine-DNA methyltransferase (

Authors

• Patricia Pittman
• Chen Sun
• Timothy Samec
• Christian Davidson
• David Bryant
• Iyad Alnahhas
• Michael Glantz
• Robert Hahn-Lowry
• David Spetzler
• Daniel Magee
• Theodore Nicolaides

Publication/Presentation Date

1-1-2026

Abstract

BACKGROUND:

METHODS: We have developed a method of

RESULTS: MGMTai reliably predicted

CONCLUSION: Implementation of an AI-based molecular classification system, MGMTai, can better describe

Volume

8

Issue

1

First Page

103

Last Page

103

ISSN

2632-2498

Published In/Presented At

Pittman, P., Sun, C., Samec, T., Davidson, C., Bryant, D., Alnahhas, I., Glantz, M., Hahn-Lowry, R., Spetzler, D., Magee, D., & Nicolaides, T. (2026). MGMTai: O6-methylguanine-DNA methyltransferase (MGMT) methylation prediction in isocitrate dehydrogenase (IDH)-wild type glioblastoma to direct temozolomide therapy. Neuro-oncology advances, 8(1), vdag103. https://doi.org/10.1093/noajnl/vdag103

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

42131790

Department(s)

Administration and Leadership

Document Type

Article