Ossified ligamentum flavum causing spinal cord compression in a patient with acromegaly.
Publication/Presentation Date
11-1-2013
Abstract
Acromegaly is a relatively rare neuroendocrine disorder associated with diffuse hypertrophy of bony and soft tissues due to growth hormone hypersecretion from a pituitary adenoma. Acromegaly can also cause numerous pathological changes in the spine, including degenerative osteoarticular disease, axial arthropathy, spinal stenosis, vertebral fracture and diffuse idiopathic skeletal hyperostosis (Forestier's disease). Ossified ligamentum flavum (OLF) is a rare disorder that often presents as thoracic spinal stenosis, but to our knowledge has never been described in patients with acromegaly. Previously, no link has been established between these two entities. We present, to our knowledge, the first reported case of OLF in a patient with acromegaly who presented with thoracic spinal cord compression. OLF is a potential spinal manifestation of acromegaly and should be considered in the differential diagnosis of spinal stenosis or spinal cord compression in the context of growth hormone hypersecretion.
Volume
20
Issue
11
First Page
1599
Last Page
1603
ISSN
1532-2653
Published In/Presented At
Schmidt, R. F., Goldstein, I. M., & Liu, J. K. (2013). Ossified ligamentum flavum causing spinal cord compression in a patient with acromegaly. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 20(11), 1599–1603. https://doi.org/10.1016/j.jocn.2012.10.033
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
23706185
Department(s)
Administration and Leadership
Document Type
Article