Management and outcomes of left ventricular assist device-associated endocarditis: a systematic review.
Publication/Presentation Date
11-1-2019
Abstract
BACKGROUND: Left ventricular assist device (LVAD)-associated endocarditis remains poorly studied, especially in newer continuous-flow LVADs (CF-LVADs). The aim of this review was to assess outcomes of patients with LVAD-associated endocarditis, as stratified by CF-LVAD and pulsatile LVAD (P-LVAD) use as well as by different interventions and pathogen types.
METHODS: An electronic search was performed to identify studies in the English literature on LVAD-associated endocarditis.
RESULTS: Overall, 16 articles with 26 patients were included; seven had CF-LVADs and 19 had P-LVADs; time to development of endocarditis was 91 days (152
CONCLUSIONS: Compared to patients with P-LVADs, CF-LVAD patients appeared to be resistant to early development of LVAD-associated endocarditis. There was a trend towards high survival observed amongst patients who underwent additional surgical intervention as compared to those treated with antibiotics alone, with no difference amongst surgical device exchange as compared to heart transplantation. Advantages of additional surgical intervention
Volume
8
Issue
6
First Page
600
Last Page
609
ISSN
2225-319X
Published In/Presented At
Patel, S., Rizvi, S. S. A., Choi, J. H., Horan, D. P., Weber, M. P., Maynes, E. J., Luc, J. G. Y., Aburjania, N., Entwistle, J. W., Morris, R. J., Massey, H. T., & Tchantchaleishvili, V. (2019). Management and outcomes of left ventricular assist device-associated endocarditis: a systematic review. Annals of cardiothoracic surgery, 8(6), 600–609. https://doi.org/10.21037/acs.2019.04.04
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
31832350
Department(s)
Administration and Leadership
Document Type
Article