Intestinal dilatation associated with phenothiazine therapy: a case report and literature review.

Authors

• D L Evans
• J F Rogers
• S C Peiper

Publication/Presentation Date

7-1-1979

Abstract

The authors describe a fatal episode of intestinal dilatation associated with chlorpromazine therapy. A total of 26 similar cases associated with phenothiazine or tricyclic antidepressant therapy, including 9 fatalities, has been reported in the literature. The authors cite experimental evidence supporting this association. They emphasize the difficulty of recognizing this syndrome in the psychotic patient; careful evaluation is indicated in the constipated patient who exhibits vomiting, abdominal pain, distension, or tenderness.

Volume

136

Issue

7

First Page

970

Last Page

972

ISSN

0002-953X

Published In/Presented At

Evans, D. L., Rogers, J. F., & Peiper, S. C. (1979). Intestinal dilatation associated with phenothiazine therapy: a case report and literature review. The American journal of psychiatry, 136(7), 970–972. https://doi.org/10.1176/ajp.136.7.970

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

453361

Department(s)

Administration and Leadership

Document Type

Article