Markers of cellular differentiation in acute lymphoblastic leukemia.
Publication/Presentation Date
1-1-1982
Abstract
Acute lymphoblastic leukemia (ALL) is a heterogeneous entity that can be subcategorized on the basis of morphologic aspects, immunologic markers, membrane antigens, and enzymatic content of the blast forms. Subgroups corresponding to T-cell, pre-T-cell, pre-B-cell, and non-T-, non-B-lymphocyte derivations can be defined by immunologic markers, and the biologic differences are supported by the differential expression of membrane antigens and of nuclear, lysosomal, cytoplasmic, and membrane enzymes. These studies ease the diagnosis and characterization of ALL and enhance understanding of this disease.
Volume
106
Issue
1
First Page
3
Last Page
8
ISSN
0003-9985
Published In/Presented At
Peiper, S. C., & Stass, S. A. (1982). Markers of cellular differentiation in acute lymphoblastic leukemia. Archives of pathology & laboratory medicine, 106(1), 3–8.
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
6976157
Department(s)
Administration and Leadership
Document Type
Article