Detection of Epstein-Barr virus genomes in lymphomatoid granulomatosis: analysis of 29 cases by the polymerase chain reaction technique.
Publication/Presentation Date
7-1-1990
Abstract
Twenty-nine cases of lymphomatoid granulomatosis (LYG) were examined for Epstein-Barr virus (EBV) genomes by means of the polymerase chain reaction (PCR) technique on paraffin-embedded formalin-fixed tissue. EBV DNA sequences were identified in 21 cases (72.4%), while five examples of primary well differentiated lymphocytic lymphoma (WDLL) of lung and one metastatic large cell lymphoma to lung (lymph node origin) were negative. These findings support the hypothesis that LYG represents a unique form of lymphoma, and they suggest that its pathogenesis may be related to EBV infection.
Volume
3
Issue
4
First Page
435
Last Page
441
ISSN
0893-3952
Published In/Presented At
Katzenstein, A. L., & Peiper, S. C. (1990). Detection of Epstein-Barr virus genomes in lymphomatoid granulomatosis: analysis of 29 cases by the polymerase chain reaction technique. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 3(4), 435–441.
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
2170969
Department(s)
Administration and Leadership
Document Type
Article