Malignant rhabdoid tumor of the liver. Evidence for epithelial differentiation.

Authors

• D M Parham
• S C Peiper
• G Robicheaux
• R C Ribeiro
• E C Douglass

Publication/Presentation Date

1-1-1988

Abstract

Malignant rhabdoid tumors most commonly occur in the kidney. Rarely does this tumor arise in extrarenal sites; a single documented primary hepatic tumor has been described. We describe two patients who had malignant tumors arising in the liver. These tumors demonstrated cytologic, histologic, and ultrastructural features typical of malignant rhabdoid tumor. By immunohistochemistry, the tumor cells from both patients expressed the epithelial membrane antigen, cytokeratin, and vimentin and cells from one patient contained alpha 1-antitrypsin. Neither patient had evidence of renal involvement at autopsy. Thus, we demonstrate that this rapidly fatal tumor contains cells showing features of epithelial differentiation, and that it may occur as a primary hepatic tumor.

Volume

112

Issue

1

First Page

61

Last Page

64

ISSN

0003-9985

Published In/Presented At

Parham, D. M., Peiper, S. C., Robicheaux, G., Ribeiro, R. C., & Douglass, E. C. (1988). Malignant rhabdoid tumor of the liver. Evidence for epithelial differentiation. Archives of pathology & laboratory medicine, 112(1), 61–64.

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

2447852

Department(s)

Administration and Leadership

Document Type

Article