Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs.

Authors

• Hirokazu Tamamura
• Hiroshi Tsutsumi
• Hiroyuki Masuno
• Satoko Mizokami
• Kenichi Hiramatsu
• Zixuan Wang
• John O Trent
• Hideki Nakashima
• Naoki Yamamoto
• Stephen C Peiper
• Nobutaka Fujii

Publication/Presentation Date

6-21-2006

Abstract

A linear type of several low molecular weight CXCR4 antagonists were developed based on T140 analogs, which were previously found to be strong CXCR4 antagonists that block X4-HIV-1 entry and have inhibitory activities against cancer metastasis/progression and rheumatoid arthritis.

Volume

4

Issue

12

First Page

2354

Last Page

2357

ISSN

1477-0520

Published In/Presented At

Tamamura, H., Tsutsumi, H., Masuno, H., Mizokami, S., Hiramatsu, K., Wang, Z., Trent, J. O., Nakashima, H., Yamamoto, N., Peiper, S. C., & Fujii, N. (2006). Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs. Organic & biomolecular chemistry, 4(12), 2354–2357. https://doi.org/10.1039/b603818b

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

16763678

Department(s)

Administration and Leadership

Document Type

Article