Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report.

Authors

• R Shapiro
• M L Jordan
• V P Scantlebury
• J J Fung
• C Jensen
• C Vivas
• J McCauley
• W D Irish
• S Mitchell
• A J Demetris

Publication/Presentation Date

2-1-1993

Abstract

FK 506 was used as a primary immunosuppressive agent in 125 cases of renal transplantation in a randomized trial comparing FK 506/prednisone with FK 506/azathioprine/prednisone. With a mean follow-up of 5.5 +/- 2.5 months, there has been a 6-month actuarial patient survival of 99% and graft survival of 88%. There is no difference thus far between the two-drug and three-drug groups, although there may be less rejection and diabetes in the three-drug group. These results suggest that FK 506 is a useful immunosuppressive agent in kidney transplantation.

Volume

25

Issue

1 Pt 1

First Page

669

Last Page

672

ISSN

0041-1345

Published In/Presented At

Shapiro, R., Jordan, M. L., Scantlebury, V. P., Fung, J. J., Jensen, C., Vivas, C., McCauley, J., Irish, W. D., Mitchell, S., & Demetris, A. J. (1993). Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report. Transplantation proceedings, 25(1 Pt 1), 669–672.

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

7679836

Department(s)

Administration and Leadership

Document Type

Article