Expert consensus for multi-modality imaging evaluation of cardiovascular complications of radiotherapy in adults: a report from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.

Authors

• Patrizio Lancellotti
• Vuyisile T Nkomo
• Luigi P Badano
• Jutta Bergler-Klein
• Jan Bogaert
• Laurent Davin
• Bernard Cosyns
• Philippe Coucke
• Raluca Dulgheru
• Thor Edvardsen
• Oliver Gaemperli
• Maurizio Galderisi
• Brian Griffin
• Paul A Heidenreich
• Koen Nieman
• Juan C Plana
• Steven C Port
• Marielle Scherrer-Crosbie
• Ronald G Schwartz
• Igal A Sebag
• Jens-Uwe Voigt
• Samuel Wann
• Phillip C Yang

Publication/Presentation Date

8-1-2013

Abstract

Cardiac toxicity is one of the most concerning side effects of anti-cancer therapy. The gain in life expectancy obtained with anti-cancer therapy can be compromised by increased morbidity and mortality associated with its cardiac complications. While radiosensitivity of the heart was initially recognized only in the early 1970s, the heart is regarded in the current era as one of the most critical dose-limiting organs in radiotherapy. Several clinical studies have identified adverse clinical consequences of radiation-induced heart disease (RIHD) on the outcome of long-term cancer survivors. A comprehensive review of potential cardiac complications related to radiotherapy is warranted. An evidence-based review of several imaging approaches used to detect, evaluate, and monitor RIHD is discussed. Recommendations for the early identification and monitoring of cardiovascular complications of radiotherapy by cardiac imaging are also proposed.

Volume

14

Issue

8

First Page

721

Last Page

740

ISSN

2047-2412

Published In/Presented At

Lancellotti, P., Nkomo, V. T., Badano, L. P., Bergler-Klein, J., Bogaert, J., Davin, L., Cosyns, B., Coucke, P., Dulgheru, R., Edvardsen, T., Gaemperli, O., Galderisi, M., Griffin, B., Heidenreich, P. A., Nieman, K., Plana, J. C., Port, S. C., Scherrer-Crosbie, M., Schwartz, R. G., Sebag, I. A., … Society of Cardiovascular Computed Tomography (2013). Expert consensus for multi-modality imaging evaluation of cardiovascular complications of radiotherapy in adults: a report from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. European heart journal. Cardiovascular Imaging, 14(8), 721–740. https://doi.org/10.1093/ehjci/jet123

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

23847385

Department(s)

Administration and Leadership

Document Type

Article