[Chemotherapy and the heart].
Publication/Presentation Date
5-1-2011
Abstract
The improvements in cancer detection and therapy have created a new cohort of patients who will experience sufficient survival to develop the cardiac complications of the cancer therapy. Three-dimensional echocardiography has been validated as the ultrasound modality with the best accuracy for the calculation of ejection fraction when compared to magnetic resonance imaging, the current gold standard, making it the tool of choice, when available, for the initial evaluation and follow up of the patient receiving chemotherapy. If three-dimensional echocardiography is not available, or if the quality of the images is inadequate, the use of ultrasound contrast can be useful for the definition of the endocardial border and identification of the true apex of the heart, enhancing the ability of the interpreter to accurately calculate volumes and ejection fraction. Two-dimensional strain appears promising as a tool to identify abnormalities in myocardial mechanics very early on during cardiotoxicity, allowing the prediction of later overt systolic dysfunction. This parameter may be useful in the detection of chemotherapy treated patients who could benefit from alternate therapies, thereby decreasing the incidence of cardiotoxicity and its associated morbidity and mortality.
Volume
64
Issue
5
First Page
409
Last Page
415
ISSN
1579-2242
Published In/Presented At
Plana J. C. (2011). La quimioterapia y el corazón [Chemotherapy and the heart]. Revista espanola de cardiologia, 64(5), 409–415. https://doi.org/10.1016/j.recesp.2010.12.013
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
21492985
Department(s)
Administration and Leadership
Document Type
Article