Management of Patients with Acute Coronary Syndrome and Cancer.
Publication/Presentation Date
10-10-2020
Abstract
Cancer patients with acute coronary syndrome (ACS) have significantly greater mortality compared with non-cancer patients. This risk is partly directly attributable to the malignancy; however these patients are frequently undertreated with respect to guideline recommended treatments for ACS due to higher bleeding risks from anemia and thrombocytopenia. Due to exclusion from large clinical trials, there is a paucity of data regarding how to best treat these complex and high-risk patients. PURPOSE OF REVIEW: To review the literature and identify risk factors among cancer patients associated with poor outcomes, pathophysiology of chemotherapy and radiation therapy contributing to accelerated coronary artery disease and ACS, and data regarding outcomes with medical therapy and invasive management. RECENT FINDINGS: Despite an elevated bleeding risk, many cancer patients may benefit from ACC/AHA guideline-directed management for ACS including aspirin, P2Y
Volume
22
Issue
12
First Page
159
Last Page
159
ISSN
1534-3170
Published In/Presented At
Moran, T. B., & Plana, J. C. (2020). Management of Patients with Acute Coronary Syndrome and Cancer. Current cardiology reports, 22(12), 159. https://doi.org/10.1007/s11886-020-01409-8
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
33037951
Department(s)
Administration and Leadership
Document Type
Article