Deceased-donor acute kidney injury is not associated with kidney allograft failure.
Publication/Presentation Date
1-1-2019
Abstract
Deceased-donor acute kidney injury (AKI) is associated with organ discard and delayed graft function, but data on longer-term allograft survival are limited. We performed a multicenter study to determine associations between donor AKI (from none to severe based on AKI Network stages) and all-cause graft failure, adjusting for donor, transplant, and recipient factors. We examined whether any of the following factors modified the relationship between donor AKI and graft survival: kidney donor profile index, cold ischemia time, donation after cardiac death, expanded-criteria donation, kidney machine perfusion, donor-recipient gender combinations, or delayed graft function. We also evaluated the association between donor AKI and a 3-year composite outcome of all-cause graft failure or estimated glomerular filtration rate ≤ 20 mL/min/1.73 m
Volume
95
Issue
1
First Page
199
Last Page
209
ISSN
1523-1755
Published In/Presented At
Hall, I. E., Akalin, E., Bromberg, J. S., Doshi, M. D., Greene, T., Harhay, M. N., Jia, Y., Mansour, S. G., Mohan, S., Muthukumar, T., Reese, P. P., Schröppel, B., Singh, P., Thiessen-Philbrook, H. R., Weng, F. L., & Parikh, C. R. (2019). Deceased-donor acute kidney injury is not associated with kidney allograft failure. Kidney international, 95(1), 199–209. https://doi.org/10.1016/j.kint.2018.08.047
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
30470437
Department(s)
Administration and Leadership
Document Type
Article