Improvement in aerobic capacity after an exercise program in sporadic inclusion body myositis.
Publication/Presentation Date
6-1-2009
Abstract
OBJECTIVES: The study aimed to investigate the effects of a combined functional and aerobic exercise program on aerobic capacity, muscle strength, and functional mobility in a group of patients with sporadic inclusion body myositis (IBM).
METHODS: Aerobic capacity, muscle strength, and functional capacity assessments were conducted on 7 participants with sporadic IBM before and after a 12-week exercise program, which included resistance exercises and aerobic stationary cycling 3 times per week on alternative days.
RESULTS: Aerobic capacity of the group increased significantly by 38%, and significant strength improvements were observed in 4 of the muscle groups tested (P < 0.05). The exercise program was well tolerated, and there was no significant change in the serum creatine kinase level after the exercise period.
CONCLUSIONS: An aerobic exercise program can be safely tolerated by patients with sporadic IBM and can improve aerobic capacity and muscle strength when combined with resistance training. These findings indicate that aerobic and functional muscle strengthening exercise should be considered in the management of patients with IBM.
Volume
10
Issue
4
First Page
178
Last Page
184
ISSN
1537-1611
Published In/Presented At
Johnson, L. G., Collier, K. E., Edwards, D. J., Philippe, D. L., Eastwood, P. R., Walters, S. E., Thickbroom, G. W., & Mastaglia, F. L. (2009). Improvement in aerobic capacity after an exercise program in sporadic inclusion body myositis. Journal of clinical neuromuscular disease, 10(4), 178–184. https://doi.org/10.1097/CND.0b013e3181a23c86
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
19494728
Department(s)
Administration and Leadership
Document Type
Article