Long-term repetitive transcranial magnetic stimulation therapy: new research questions arising from one tinnitus case?
Publication/Presentation Date
12-23-2014
Abstract
Tinnitus may become refractory to treatment and disabling. Brain transcranial magnetic stimulation (TMS) has shown promise as a therapy, but has been employed primarily short-term. We treated a patient with 5 weeks of weekly repetitive TMS (rTMS), followed by 6 months of monthly rTMS. He was a 75-year-old dentist with chronic tinnitus from occupational noise exposure. Physical examination and MRIs of the auditory canals and brain had revealed no lesions. The patient showed a general gradual, progressive improvement on per cent of severe tinnitus diary days (from baseline 100% to 33%), tinnitus handicap inventory (from baseline score 70 to 18), and mini-tinnitus questionnaire (from baseline score 17 to 6). No changes occurred in serial audiograms. Transient adverse events were a headache during stimulation, and dizziness 30 min after treatment. Implications and questions for future non-invasive neuromodulation clinical research raised by our case are discussed.
Volume
2014
ISSN
1757-790X
Published In/Presented At
Labar, D. R., Cortes, M., & Edwards, D. (2014). Long-term repetitive transcranial magnetic stimulation therapy: new research questions arising from one tinnitus case?. BMJ case reports, 2014, bcr2014207203. https://doi.org/10.1136/bcr-2014-207203
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
25538216
Department(s)
Administration and Leadership
Document Type
Article