Cardiac sarcoidosis a brief review of the evolving role of diagnostic imaging.
Publication/Presentation Date
3-1-2026
Abstract
Cardiac Sarcoidosis (CS) is a potentially life-threatening manifestation of sarcoidosis that presents significant diagnostic and management challenges. While only 2-5 % of patients with sarcoidosis are diagnosed with CS, autopsy studies have demonstrated a prevalence as high as 25 % suggesting the condition is often under recognized likely because of lack of or nonspecific symptoms or diagnostic limitations. Considering the unreliability and invasiveness of endomyocardial biopsy, cardiac magnetic resonance imaging (CMR) and Fluorodeoxyglucose F18 (FDG) positron emission tomography (PET) have become useful diagnostic modalities in suspected cases of CS. However, there is scarce data in support of one imaging modality over the other and each has its limitations. Such limitations are depicted in the case of a patient with complete heart block and newly diagnosed sarcoidosis showing conflicting results on FDG-PET and CMR. A narrative review of current knowledge on this condition and about the imaging modalities available for the workup of CS is provided.
Volume
371
Issue
3
First Page
281
Last Page
285
ISSN
1538-2990
Published In/Presented At
Venkatesan, B., Roman, J., & Kramer, D. (2026). Cardiac sarcoidosis a brief review of the evolving role of diagnostic imaging. The American journal of the medical sciences, 371(3), 281–285. https://doi.org/10.1016/j.amjms.2025.10.024
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
41177510
Department(s)
Administration and Leadership
Document Type
Article