Nonsteroidal anti-inflammatory drugs: are they safe after joint arthroplasty for early pain?
Publication/Presentation Date
1-1-2007
Abstract
A significant proportion of patients will experience moderate to severe pain after hip or knee replacement surgery. Multimodal pain control regimens have been developed to address this issue. These regimens may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Concern over excessive bleeding in the perioperative period, especially in joint arthroplasty patients receiving anticoagulation therapy, generally prohibits the use of nonspecific NSAIDs. Cyclooxygenase-2 inhibitors, a class of NSAIDs, are not believed to increase the risk of bleeding and may be useful in this population of patients. However, recent research shows increased cardiovascular and renal risks with cyclooxygenase-2 inhibitors and has limited their use for postoperative pain control in joint arthroplasty patients.
Volume
56
First Page
133
Last Page
137
ISSN
0065-6895
Published In/Presented At
Purtill J. J. (2007). Nonsteroidal anti-inflammatory drugs: are they safe after joint arthroplasty for early pain?. Instructional course lectures, 56, 133–137.
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
17472301
Department(s)
Administration and Leadership
Document Type
Article