Medication Complications in Extracorporeal Membrane Oxygenation.
Publication/Presentation Date
10-1-2017
Abstract
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics. These changes can lead to exposure-driven decreases in efficacy or increased incidence of side effects. The pharmacokinetic changes are drug specific and largely undefined for most drugs. We review available drug dosing data and provide guidance for use in the ECMO patient population.
Volume
33
Issue
4
First Page
897
Last Page
920
ISSN
1557-8232
Published In/Presented At
Shah, A. G., Peahota, M., Thoma, B. N., & Kraft, W. K. (2017). Medication Complications in Extracorporeal Membrane Oxygenation. Critical care clinics, 33(4), 897–920. https://doi.org/10.1016/j.ccc.2017.06.010
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
28887935
Department(s)
Administration and Leadership
Document Type
Article