Macrophage uptake rate of Sonazoid in breast lymphosonography is highly conserved in healthy controls.
Publication/Presentation Date
10-4-2024
Abstract
Subcutaneous microbubble administration in connection with contrast enhanced ultrasound (CEUS) imaging is showing promise as a noninvasive and sensitive way to detect tumor draining sentinel lymph nodes (SLNs) in patients with breast cancer. Moreover, there is potential to harness the results from these approaches to directly estimate cancer burden, since some microbubble formulas, such as the Sonazoid used in this study, are rapidly phagocytosed by macrophages, and the macrophage concentration in a lymph node is inversely related to the cancer burden. This work presents a mathematical model that can approximate a rate constant governing macrophage uptake of Sonazoid,
Volume
69
Issue
20
ISSN
1361-6560
Published In/Presented At
Tichauer, K. M., Machado, P., Liu, J. B., Sarathchandra, A. S. C., Stanczak, M., Kraft, W. K., & Forsberg, F. (2024). Macrophage uptake rate of Sonazoid in breast lymphosonography is highly conserved in healthy controls. Physics in medicine and biology, 69(20), 10.1088/1361-6560/ad7f1c. https://doi.org/10.1088/1361-6560/ad7f1c
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
39317237
Department(s)
Administration and Leadership
Document Type
Article