The role of extracorporeal life support for patients with COVID-19: Preliminary results from a statewide experience.
Publication/Presentation Date
7-1-2020
Abstract
OBJECTIVE: There is a paucity of clinical data on critically ill patients with COVID-19 requiring extracorporeal life support.
METHODS: A statewide multi-institutional collaborative for COVID-19 patients was utilized to obtain clinical data on the first 10 critically ill COVID-19 patients who required extracorporeal membrane oxygenation (ECMO).
RESULTS: Of the first 10 patients that required ECMO for COVID-19, the age ranged from 31 to 62 years with the majority (70%) being men. Seven (70%) had comorbidities. The majority (80%) of patients had known sick contact and exposure to COVID-19 positive patients or traveled to pandemic areas inside the United States within the 2 weeks before symptom onset. None of the patients were healthcare workers. The most common symptoms leading to the presentation were high fever ≥103°F (90%), cough (80%) and dyspnea (70%), followed by fatigue and gastrointestinal symptoms (both 30%), myalgia, loss of taste, pleuritic chest pain, and confusion (all 10%). All patients had bilateral infiltrates on chest X-rays suggestive of interstitial viral pneumonia. All patients were cannulated in the venovenous configuration. Two (20%) patients were successfully liberated from ECMO support after 7 and 10 days, respectively, and one (10%) patient is currently on a weaning course. One patient (10%) died after 9 days on ECMO from multiorgan dysfunction.
CONCLUSIONS: These preliminary multi-institutional data from a statewide collaborative offer insight into the clinical characteristics of the first 10 patients requiring ECMO for COVID-19 and their initial clinical course. Greater morbidity and mortality is likely to be seen in these critically ill patients with longer follow-up.
Volume
35
Issue
7
First Page
1410
Last Page
1413
ISSN
1540-8191
Published In/Presented At
Sultan, I., Habertheuer, A., Usman, A. A., Kilic, A., Gnall, E., Friscia, M. E., Zubkus, D., Hirose, H., Sanchez, P., Okusanya, O., Szeto, W. Y., & Gutsche, J. (2020). The role of extracorporeal life support for patients with COVID-19: Preliminary results from a statewide experience. Journal of cardiac surgery, 35(7), 1410–1413. https://doi.org/10.1111/jocs.14583
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
32333431
Department(s)
Administration and Leadership
Document Type
Article