Characteristics of Malignant Pleural Effusion Resident CD8

Authors

• Rajeev Dhupar
• Olugbenga T Okusanya
• Seth H Eisenberg
• Sara E Monaco
• Ayana T Ruffin
• Dongyan Liu
• James D Luketich
• Udai S Kammula
• Tullia C Bruno
• Michael T Lotze
• Adam C Soloff

Publication/Presentation Date

8-27-2020

Abstract

While T cell-based cancer immunotherapies have shown great promise, there remains a need to understand how individual metastatic tumor environments impart local T cell dysfunction. At advanced stages, cancers that metastasize to the pleural space can result in a malignant pleural effusion (MPE) that harbors abundant tumor and immune cells, often exceeding 10

Volume

21

Issue

17

ISSN

1422-0067

Published In/Presented At

Dhupar, R., Okusanya, O. T., Eisenberg, S. H., Monaco, S. E., Ruffin, A. T., Liu, D., Luketich, J. D., Kammula, U. S., Bruno, T. C., Lotze, M. T., & Soloff, A. C. (2020). Characteristics of Malignant Pleural Effusion Resident CD8+ T Cells from a Heterogeneous Collection of Tumors. International journal of molecular sciences, 21(17), 6178. https://doi.org/10.3390/ijms21176178

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

32867034

Department(s)

Administration and Leadership

Document Type

Article