Using Postactivation Adjustment as a Marker for Inferior Outcomes in Hypoglossal Nerve Stimulator Patients.

Publication/Presentation Date

3-1-2025

Abstract

OBJECTIVE: This study aimed to examine differences in postoperative outcomes between patients requiring postactivation adjustment and those who do not, within a cohort of patients undergoing hypoglossal nerve stimulation (HGNS) for obstructive sleep apnea (OSA).

STUDY DESIGN: Retrospective database analysis.

SETTING: Single-institution, academic center.

METHODS: We reviewed patients undergoing HGNS placement for OSA from January 2020 to December 2021. Adjustment visits were defined as any visit that occurred after the initial activation of the device but before postoperative sleep study, including modification of the HGNS device settings (stimulation voltage, configuration, pulse width, rate, start, and pause delay). Primary outcome measures included postoperative apnea-hypopnea index (AHI) and O

RESULTS: Of 116 patients undergoing HGNS placement, 30 (25.6%) required postactivation adjustment. These patients had a higher average postoperative AHI of 21.3, compared to 12.5 in those who did not undergo adjustments (P = .002). Additionally, adjustment patients had a significantly lower postoperative O

CONCLUSION: Patients experiencing early postactivation HGNS intolerance, requiring device adjustment, have significantly poorer long-term surgical sleep outcomes for OSA. Early identification of this cohort is crucial to optimizing treatment for those less responsive to HGNS therapy.

Volume

172

Issue

3

First Page

1063

Last Page

1068

ISSN

1097-6817

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

39709537

Department(s)

Administration and Leadership

Document Type

Article

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