Changes in Hypoxemia Metrics After Upper Airway Surgery for Obstructive Sleep Apnea.
Publication/Presentation Date
5-1-2025
Abstract
OBJECTIVE: The apnea-hypopnea index (AHI) quantifies obstructive sleep apnea (OSA) severity but has limited correlation with subjective symptoms and cardiovascular risk. Sleep parameters related to oxygenation status and hypoxic burden may offer utility as additional predictors of cardiovascular risk and the physiologic consequences of OSA. This study aims to assess the change in measures of oxygenation status following sleep surgery for OSA.
STUDY DESIGN: A retrospective cohort study.
SETTING: A single-institution tertiary care center.
METHODS: Patients who underwent hypoglossal nerve stimulator (HGNS) placement, expansion sphincter pharyngoplasty (ESP), or maxillomandibular advancement (MMA) for continuous positive airway pressure-intolerant OSA were included. The percentage of sleep time below SaO
RESULTS: A total of 219 patients were included (65% HGNS, 24% ESP, 11% MMA). The average decline in AHI and ESS was 11.9 events/h (standard deviation [SD] = 19.9, P < .001) and 3.2 points (SD = 4.7, P < .001), respectively. Among measures of sleep oxygenation, pT90 (11.5 → 8.9, P < .001), oxygen desaturation index (27.1 → 15.1, P < .001), and SpO
CONCLUSION: Upper airway surgery improves metrics of oxygen status in addition to the AHI. Changes in pT90 correlate with subjective symptoms of OSA per ESS, suggesting utility in capturing disease burden.
Volume
172
Issue
5
First Page
1781
Last Page
1788
ISSN
1097-6817
Published In/Presented At
Kaki, P. C., Goldfarb, J. A., Snyder, N. P., Sina, E. M., Kaffenberger, T. M., Creighton, E., Molin, N., Boon, M., & Huntley, C. (2025). Changes in Hypoxemia Metrics After Upper Airway Surgery for Obstructive Sleep Apnea. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 172(5), 1781–1788. https://doi.org/10.1002/ohn.1182
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
40052332
Department(s)
Administration and Leadership
Document Type
Article