Episcleritis and scleritis: clinical features and treatment results.
Publication/Presentation Date
10-1-2000
Abstract
PURPOSE: To evaluate the clinical experience with episcleritis and scleritis at a tertiary care eye center.
METHODS: Retrospective chart review.
RESULTS: One hundred thirty-four patients with scleral inflammation were seen over a 12-year period. Thirty-seven patients had episcleritis, and 97 patients had scleritis. Ocular complications occurred in only 13.5% of patients with episcleritis but in 58.8% of patients with scleritis (P < .0001). No patient with episcleritis had a decrease in visual acuity, whereas 15.9% of patients with scleritis did. Only 16.7% of patients with episcleritis required more than topical corticosteroids for treatment, and these patients required oral nonsteroidal anti-inflammatory drugs. Conversely, 30.4% of patients with scleritis required nonsteroidal anti-inflammatory drugs, 31.9% oral prednisone, and 26.1% systemic immunosuppressive drugs (P < .0001). Necrotizing scleritis and posterior scleritis more often were associated with ocular complications, occurring in 91.7% and 85.7%, respectively, than were diffuse anterior scleritis and nodular anterior scleritis (P =.020). Patients with necrotizing scleritis and posterior scleritis were more likely to be treated with oral corticosteroids or immunosuppressive drugs (90% and 100%, respectively) than were patients with diffuse anterior scleritis and nodular anterior scleritis (56.4% and 21.4%, respectively, P =.002).
CONCLUSIONS: Scleritis is a severe ocular inflammation, often associated with ocular complications, and nearly always treated with systemic medications. Nearly 60% of these patients will need oral corticosteroids or immunosuppressive drugs to control the disease.
Volume
130
Issue
4
First Page
469
Last Page
476
ISSN
0002-9394
Published In/Presented At
Jabs, D. A., Mudun, A., Dunn, J. P., & Marsh, M. J. (2000). Episcleritis and scleritis: clinical features and treatment results. American journal of ophthalmology, 130(4), 469–476. https://doi.org/10.1016/s0002-9394(00)00710-8
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
11024419
Department(s)
Administration and Leadership
Document Type
Article