Visual function in prolactinoma patients treated with bromocriptine.
Publication/Presentation Date
10-1-1985
Abstract
Ten patients with prolactin-secreting pituitary adenomas (prolactinoma) and visual dysfunction were treated primarily with bromocriptine. Nine patients had improvement of visual field or acuity associated with computed tomography (CT) evidence of a decrease in tumor size and reduction of serum prolactin level (SPL). Visual improvement usually began within days of commencing bromocriptine therapy. One patient with initial improvement had a worsening of visual fields at 11 months despite a normal SPL and a stable CT appearance of tumor size. This patient and the single patient without visual improvement underwent trans-sphenoidal hypophysectomy (TSH), but neither patient had postoperative visual improvement. Two other patients underwent TSH for nonvisual reasons. The remaining six patients have maintained excellent visual function at last follow-up (average of 18 months on bromocriptine therapy). This study shows that bromocriptine is an effective short- and long-term therapy for most patients with visual dysfunction due to prolactinoma.
Volume
92
Issue
10
First Page
1332
Last Page
1341
ISSN
0161-6420
Published In/Presented At
Moster, M. L., Savino, P. J., Schatz, N. J., Snyder, P. J., Sergott, R. C., & Bosley, T. M. (1985). Visual function in prolactinoma patients treated with bromocriptine. Ophthalmology, 92(10), 1332–1341. https://doi.org/10.1016/s0161-6420(85)33853-8
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
4069600
Department(s)
Administration and Leadership
Document Type
Article