A color Doppler analysis of nifedipine-induced posterior ocular blood flow changes in open-angle glaucoma.

Authors

• R P Wilson
• W J Chang
• R C Sergott
• M R Moster
• C M Schmidt
• J B Bond
• A Harris

Publication/Presentation Date

8-1-1997

Abstract

PURPOSE: This pilot study used color Doppler imaging to investigate the effects of nifedipine on the posterior ocular blood flow of patients with glaucoma progression at normal intraocular pressures.

PATIENTS AND METHODS: Eighteen patients, 11 men and seven women with a median age of 61.7 years, were imaged before and 6 weeks after the initiation of 30 mg of sustained-release nifedipine (Procardia XL; produced by either Pfizer or Pratt) daily.

RESULTS: There was no statistically significant change in the blood velocity of the ophthalmic artery, central retinal artery, and main nasal and temporal short posterior ciliary arteries after treatment with nifedipine.

CONCLUSION: The routine use of nifedipine in patients with normal tension glaucoma progression is not supported by this study.

Volume

6

Issue

4

First Page

231

Last Page

236

ISSN

1057-0829

Published In/Presented At

Wilson, R. P., Chang, W. J., Sergott, R. C., Moster, M. R., Schmidt, C. M., Bond, J. B., & Harris, A. (1997). A color Doppler analysis of nifedipine-induced posterior ocular blood flow changes in open-angle glaucoma. Journal of glaucoma, 6(4), 231–236.

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

9264302

Department(s)

Administration and Leadership

Document Type

Article