The prevalence of cupping in end-stage arteritic and nonarteritic anterior ischemic optic neuropathy.

Publication/Presentation Date

3-1-2001

Abstract

OBJECTIVE: To evaluate the prevalence of cupping in arteritic anterior ischemic optic neuropathy (AAION) and nonarteritic anterior ischemic optic neuropathy (NAION).

DESIGN: Retrospective, observational case series.

PARTICIPANTS: Three hundred one patients.

METHODS: Review of clinical records and color fundus photographs.

MAIN OUTCOME MEASURES: Photographic and clinical interpretation of optic nerve appearance.

RESULTS: Ninety-two patients with AAION and 102 with NAION were included in the study. Disc photographs of 42 patients (48%) with AAION and 32 patients (31%) with NAION were available for reassessment. These were presented in a masked fashion along with a random sample of 27 disc pairs considered to be 'normal' and 27 disc pairs with 'established glaucoma' according to two examiners. Cupping was present in 92% of eyes with AAION secondary to giant cell arteritis and in 2% of eyes with NAION (kappa = 0.96; P < 0.001).

CONCLUSIONS: The end-stage optic disc appearance in AAION secondary to giant cell arteritis is cupping, whereas segmental or diffuse pallor without cupping is the typical disc appearance after NAION.

Volume

108

Issue

3

First Page

593

Last Page

598

ISSN

0161-6420

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

11237915

Department(s)

Administration and Leadership

Document Type

Article

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