Recovery of visual function in patients with biopsy-proven giant cell arteritis.
Publication/Presentation Date
3-1-2003
Abstract
OBJECTIVE: To assess the visual function of patients with giant cell arteritis (GCA) who had visual loss from either anterior ischemic optic neuropathy (AION) or central retinal artery occlusion and had a subsequent improvement in visual acuity after treatment with corticosteroids.
DESIGN: Retrospective, observational case series.
PARTICIPANTS: Thirty-two consecutive patients with biopsy-proven GCA treated at one institution between January 1992 and December 1997.
INTERVENTION: Treatment with intravenous methylprednisolone 250 mg every 6 hours for 3 days, followed by oral prednisone 1 mg/kg daily for at least 4 weeks duration.
MAIN OUTCOME MEASURES: The number of patients with an improvement in visual acuity after treatment with intravenous methylprednisolone; neuro-ophthalmic evaluation, including visual acuity, funduscopy, and visual field examination of these patients.
RESULTS: Improvement in visual acuity occurred in 5 of 39 eyes (13%) with visual loss from biopsy-proven GCA, and all 5 patients had AION. Despite the improvement of visual acuity in these 5 patients, perimetry revealed marked constriction of the visual field in each affected eye.
CONCLUSIONS: The prognosis for visual improvement in GCA is poor. Although an improvement in visual acuity occurred in 5 of our patients, marked constriction of the visual field was present in all of them.
Volume
110
Issue
3
First Page
539
Last Page
542
ISSN
0161-6420
Published In/Presented At
Foroozan, R., Deramo, V. A., Buono, L. M., Jayamanne, D. G., Sergott, R. C., Danesh-Meyer, H., & Savino, P. J. (2003). Recovery of visual function in patients with biopsy-proven giant cell arteritis. Ophthalmology, 110(3), 539–542. https://doi.org/10.1016/S0161-6420(02)01775-X
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
12623817
Department(s)
Administration and Leadership
Document Type
Article