Multifocal ERG in ethambutol associated visual loss.
Publication/Presentation Date
8-1-2005
Abstract
AIM: To determine the anatomical site and extent of electrophysiological dysfunction in patients with ethambutol associated visual loss.
METHODS: A comparative case series. Four patients with ethambutol associated visual loss underwent multifocal electroretinography (mERG). Two patients had advanced visual loss while two had early signs of toxicity. The N1-P1, N1, P1 amplitudes, N1, and P1 latencies were compared to 10 age and sex matched controls.
RESULTS: mERG abnormalities were detected in the ethambutol treated patients. The N1 amplitude was significantly lower in the ethambutol treated patients than in the control group.
CONCLUSION: Ethambutol is possibly toxic to the retina, and not only the optic nerve. The multifocal ERG may be of value to diagnose and monitor patients taking ethambutol.
Volume
89
Issue
8
First Page
976
Last Page
982
ISSN
0007-1161
Published In/Presented At
Behbehani, R. S., Affel, E. L., Sergott, R. C., & Savino, P. J. (2005). Multifocal ERG in ethambutol associated visual loss. The British journal of ophthalmology, 89(8), 976–982. https://doi.org/10.1136/bjo.2004.065656
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
16024847
Department(s)
Administration and Leadership
Document Type
Article