Is Hypertension Associated with Worse Renal Functional Outcomes after Minimally Invasive Partial Nephrectomy? Results from a Multi-Institutional Cohort.
Publication/Presentation Date
2-25-2022
Abstract
BACKGROUND: Hypertension (HTN) is a global public health issue. There are limited data regarding the effects of HTN in patients undergoing partial nephrectomy (PN) for renal tumors. To address this void, we tested the association between HTN and renal function after minimally invasive PN (MIPN).
METHODS: Using a multi-institutional database (2007-2017), we identified patients aged ≥ 18 years with a diagnosis of cT1 renal tumors treated with MIPN. Kaplan-Meier plots and Cox regression models addressed newly-onset CKD stage ≥ 3b or higher (sCKD). All analyses were repeated after 1:1 propensity score matching (PSM).
RESULTS: Overall, 2144 patients were identified. Of those, 35% (
CONCLUSIONS: Yes-HTN patients exhibited worse renal function after MIPN when compared to their no-HTN counterparts. However, these observations need to be further tested in a prospective cohort study.
Volume
11
Issue
5
ISSN
2077-0383
Published In/Presented At
Flammia, R. S., Anceschi, U., Tufano, A., Tuderti, G., Ferriero, M. C., Brassetti, A., Mari, A., Di Maida, F., Minervini, A., Derweesh, I. H., Capitanio, U., Larcher, A., Montorsi, F., Eun, D. D., Lee, J., Luciani, L. G., Cai, T., Malossini, G., Veccia, A., Autorino, R., … Simone, G. (2022). Is Hypertension Associated with Worse Renal Functional Outcomes after Minimally Invasive Partial Nephrectomy? Results from a Multi-Institutional Cohort. Journal of clinical medicine, 11(5), 1243. https://doi.org/10.3390/jcm11051243
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
35268334
Department(s)
Administration and Leadership
Document Type
Article