Reversal of Roux-en-Y Gastric Bypass: A Multi-Centric Analysis of Indications, Techniques, and Surgical Outcomes.
Publication/Presentation Date
2-1-2025
Abstract
BACKGROUND: Roux-en-Y gastric bypass may present long-term complications that require revisional surgery or even reversal to normal anatomy. Data on the indications, surgical technique, and outcomes of RYGB reversal remain scarce.
METHODS: We identified 48 cases of RYGB reversals with complete 90-day follow-up within a multi-centric international retrospective database of elective secondary bariatric surgery. The operations were performed between 2010 and 2024 in high-volume referral centers in Europe and USA. Data were collected on body weight, associated diseases, and on surgical outcomes up to 1-year postoperatively.
RESULTS: Patients were mainly female (81.3%) with a median age of 50 years (IQR 39-56). RYGB reversal was performed 7 years (median) after primary RYGB in patients with a BMI of 23.9 kg/m
CONCLUSION: Although RYGB is a theoretically reversible procedure, normal anatomy is re-established only in selected cases which are refractory to medical therapy and often also to revisional bariatric surgery. RYGB reversals entail high morbidity, while the extent of recurrent weight gain at 1-year post-reversal seems to allow patients to remain below the threshold of severe obesity.
Volume
35
Issue
2
First Page
471
Last Page
480
ISSN
1708-0428
Published In/Presented At
Plath, L., Vannijvel, M., Okkema, S., Deleus, E., Lloyd, A., Lo Menzo, E., Tadros, G., Raguz, I., San Martin, A., Kraljević, M., Mantziari, S., Frey, S., Gensthaler, L., Sammalkorpi, H., García Galocha, J. L., Sujathan, V., Zapata, A., Tatarian, T., Wiggins, T., Bardisi, E. S., … Gero, D. (2025). Reversal of Roux-en-Y Gastric Bypass: A Multi-Centric Analysis of Indications, Techniques, and Surgical Outcomes. Obesity surgery, 35(2), 471–480. https://doi.org/10.1007/s11695-024-07650-2
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
39821905
Department(s)
Administration and Leadership
Document Type
Article